Best B12 + MIC Injection Providers Online in 2026
- Clinician-prescribed
- Shipped to your door
01
Joi + Blokes
B12 + MIC Injections From $51/mo, HSA/FSA Eligible
- Clinicians and 1:1 coaching included
- $51/mo Subscribe & Save, or $149 for a 70-day supply
Outstanding
B12 + MIC Injections From $51/mo, HSA/FSA Eligible
- Clinicians and 1:1 coaching included
- $51/mo Subscribe & Save, or $149 for a 70-day supply
Best Overall Pick
The Complete Guide to B12 + MIC Injections in 2026
The best online B12 + MIC providers have a licensed clinician approve the prescription, publish the monthly price and are honest that these are compounded wellness injections. Joi + Blokes ranks #1 in our 2026 comparison at $51 a month on Subscribe & Save, HSA/FSA eligible, with clinicians and 1:1 coaching included. PlexusDx follows from $69 a month, with nothing charged unless a provider approves.
B12 + MIC injections, often called lipo or lipotropic shots, combine vitamin B12 with methionine, inositol and choline. They are popular in weight-loss programs, though the evidence for them is thin. This guide explains what they contain, what they can and cannot do, and how to compare providers.
#1 Ranked Provider - Best Overall
What B12 + MIC Injections Do
Methionine, inositol and choline are nutrients involved in how the liver processes fat, and vitamin B12 is needed for red blood cell formation and nerve function. Combined in one injection, they are marketed to support energy and fat metabolism.
B12 injections reliably correct a B12 deficiency, but the NIH Office of Dietary Supplements notes that B12 has not been shown to boost energy or performance in people who are not deficient. There are no large trials showing that MIC injections cause weight loss on their own.
Reported Benefits
- Corrects low vitamin B12 where present
- Some users report more energy
- Often used alongside a diet or GLP-1 program
- Quick self-injection at home
- HSA/FSA eligible at some providers
Side Effects to Know
- Injection-site soreness or redness
- Mild nausea or stomach upset
- Rare allergic reactions
- Not proven to cause weight loss on their own
- Compounded product: not FDA-approved
How to Choose a B12 + MIC Provider
The formulas are similar, so compare the terms:
- Monthly price: Joi + Blokes is $51 a month on Subscribe & Save. PlexusDx starts from $69 a month, and its lowest price needs a 12-month plan.
- One-time option: Joi + Blokes sells a 70-day supply for $149 if you do not want a subscription.
- What is included: Joi + Blokes includes board-certified clinicians, 1:1 coaching and unlimited messaging.
- Charged only if approved: PlexusDx charges $0 unless a provider approves the medication, and lets you pause or cancel anytime.
- Dose transparency: Ask for the strength of each ingredient. Joi + Blokes does not state its injection dose publicly.
B12, MIC and Lipo Shots
The names overlap, so check what is in the vial.
B12 alone is a standard injection used to treat deficiency.
MIC + B12 adds methionine, inositol and choline. This is the product both providers here offer; PlexusDx sells it as a lipo shot.
With a weight-loss program lipotropic shots are an add-on, not a replacement for proven treatment. For medication with strong trial evidence, compare GLP-1 providers.
Ready to start? Joi + Blokes is our top-ranked B12/MIC pick: B12 + MIC Injections From $51/mo, HSA/FSA Eligible.
What to Expect During Your First Month
Effects, if you notice them, are subtle:
Online intake, clinician review and shipping. You are taught how to self-inject, typically once a week.
Some people report more energy; many notice little. Results depend on diet, activity and whether you were low in B12.
Decide whether it is worth continuing at the monthly price, and check your plan length before it renews.
Who Should Consider B12 + MIC
B12 + MIC injections may suit adults who are low in B12, follow a diet that limits it, or want an add-on to a structured weight-loss plan and understand the limited evidence.
They are not a treatment for obesity. Avoid them if you are allergic to any ingredient or to cobalt, and talk to your own doctor first if you are pregnant, breastfeeding or have kidney or liver disease.
B12 + MIC Pricing Breakdown
Across the two providers we compare, pricing looks like this:
Subscription
$51/month
Joi + Blokes Subscribe & Save, with free shipping.
One-Time
$149 for 70 days
Joi + Blokes one-time purchase, about $64 a month.
Plan-Based
From $69/month
PlexusDx; the lowest price needs a 12-month plan.
$51/mo on Subscribe & Save, HSA/FSA eligible, with clinicians and 1:1 coaching included.
From $69/mo through a physician-only network in all 50 states; $0 unless approved.
Our Top Recommendation
Joi + Blokes is our #1 B12 + MIC provider for 2026: $51 a month on Subscribe & Save or $149 one-time for a 70-day supply, HSA/FSA eligible, with board-certified clinicians and coaching included.
PlexusDx is a solid alternative if you want a physician-only network and no charge unless you are approved, from $69 a month. Treat either as a supporting add-on to diet, activity and any prescribed treatment rather than a weight-loss solution in itself.
Our #1 Pick - Start Today
Frequently Asked Questions (FAQ)
Joi + Blokes ranks #1 in our 2026 comparison at $51 a month on Subscribe & Save, with clinicians and coaching included. PlexusDx starts from $69 a month.
Joi + Blokes is $51 a month on subscription or $149 one-time for a 70-day supply. PlexusDx starts from $69 a month.
There is no strong evidence that they cause weight loss on their own. They are used as an add-on to diet, exercise or prescribed treatment.
Methionine, inositol and choline, three nutrients involved in fat metabolism in the liver.
No. They are compounded medications, which are not FDA-approved finished drug products.
Joi + Blokes states that both its subscription and one-time purchase are HSA/FSA eligible. Check with your plan administrator.
How We Rank Providers
Medical Oversight
Every provider must have a licensed clinician review intake before anything is prescribed.
Transparency & Pricing
Clear, published pricing with no hidden fees. We compare the renewal price, not just the intro offer.
Treatment Access
Formats, doses, state availability and how quickly you can get from intake to first shipment.
Support & Flexibility
Follow-up care, messaging, dose changes and how easy it is to pause or cancel. These are editorial scores, not customer ratings.
Independent provider research and pricing analysis
Non-clinical editorial team, see our disclosure
This page is independent editorial research, not medical advice, and has not been reviewed by a licensed clinician. B12 and MIC injections requires evaluation by a licensed healthcare professional, and a prescription is not guaranteed. Discuss your health history, medications and goals with a qualified clinician before starting any treatment.
Medical Disclaimer
The information on TreatmentPick is for education and comparison only. It is not medical advice and does not replace a consultation with a qualified healthcare professional. Every treatment listed requires evaluation by a licensed clinician, and a prescription is never guaranteed. Compounded medications are not FDA-approved, and availability varies by state and provider.
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TreatmentPick may receive compensation when readers visit or purchase through links on this page. This does not increase the cost to the reader. This compensation may influence which providers appear on this page and the order in which they appear. We also compare pricing transparency, medical oversight, treatment access and support.