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altRx at a Glance
| Our Score | 9.90 / 10 (#1 for GLP-1) |
|---|---|
| Best For | The lowest monthly price on compounded GLP-1s |
| Medications | Compounded semaglutide and tirzepatide |
| Price | Semaglutide from $89/mo; tirzepatide from $149/mo |
| Care Model | 100% online medical visit and messaging |
| Membership | None |
| Shipping | Free, discreet 2-day delivery |
| Availability | Most, but not all, U.S. states |
What Is altRx?
altRx is an online weight loss program that prescribes compounded GLP-1 medication after a telehealth visit with a licensed clinician. It earns the #1 spot in our best GLP-1 providers ranking for one reason above all: at $89 a month for semaglutide and $149 for tirzepatide, it is the lowest month-to-month price we track for either medication without a membership fee on top.
The program is deliberately simple. You complete an online medical intake, a clinician reviews your history and, if treatment is appropriate, a weekly injection kit ships to your door with vials, syringes, alcohol prep pads and step-by-step instructions. There are no clinic visits or insurance paperwork.
Both medications altRx offers belong to the GLP-1 class. Semaglutide is the active ingredient in Ozempic® and Wegovy®; tirzepatide is the active ingredient in Mounjaro® and Zepbound® and also acts on the GIP receptor. In large trials, semaglutide 2.4mg produced average weight loss of about 15% and high-dose tirzepatide about 21%, so the choice between them is mostly about how strong an effect you want and how much you want to spend.
What altRx sells is compounded, not branded. Compounded GLP-1s contain the same active ingredient but are prepared by licensed pharmacies to a prescription and are not reviewed by the FDA as finished products, which is why the FDA has published cautions about them. That trade-off is the reason the price is so much lower than brand-name pens.
Pros & Cons
Pros
- Semaglutide from $89/mo and tirzepatide from $149/mo
- No membership, insurance or hidden fees
- Buy now, pay later with Affirm, Klarna or Afterpay
- Fully online medical visit, no clinic appointments
- Free, discreet two-day delivery with a complete kit
- No commitment; cancel anytime
Cons
- Compounded medication, not an FDA-approved branded product
- Not available in every U.S. state
- Lowest monthly rate requires a longer prepaid plan
How altRx Works
Online intake
Answer questions about your weight history, health conditions and current medications.
Clinician review
A licensed clinician reviews your answers, checks for contraindications and decides whether semaglutide or tirzepatide is appropriate.
Kit delivered
If prescribed, your medication and supplies ship free in discreet packaging and typically arrive in about two days.
Ongoing support
Message the care team about side effects and dose increases as you titrate up. Pause or cancel at any time.
Safety & What to Know
GLP-1 medications most often cause digestive side effects: nausea, constipation, diarrhea and occasional vomiting, usually worst in the days after a dose increase. Eating smaller meals, slowing down and staying hydrated helps. Less common but serious risks include pancreatitis and gallbladder problems.
Do not use GLP-1s if you are pregnant or planning a pregnancy, or if you or a close relative has had medullary thyroid cancer or MEN2. Tell the clinician about every medication you take, especially insulin or sulfonylureas, which can combine with GLP-1s to cause low blood sugar.
Because the medication comes in multi-dose vials, you draw each dose with a syringe. Read the dosing instructions carefully and ask the care team if anything is unclear, since dosing errors are one of the risks the FDA has highlighted with compounded GLP-1s.
altRx Pricing
| Semaglutide, monthly | $89/mo |
|---|---|
| Semaglutide, 3 months | $85/mo ($255 total) |
| Semaglutide, 6 months | $80/mo ($480 total) |
| Semaglutide, 12 months | $75/mo ($900 total) |
| Tirzepatide | From $149/mo |
| Membership / visit fee | None |
| Shipping | Free 2-day delivery |
The headline prices are labelled a limited offer, so confirm the current price and whether it holds at your maintenance dose before you pay. Longer prepaid plans lower the monthly cost but tie up more money up front.
Who altRx Is For
A good fit if you
- Want the lowest monthly GLP-1 price without a membership
- Prefer to pay month to month and cancel anytime
- Want to spread payments with Affirm, Klarna or Afterpay
- Are comfortable with compounded medication and vials
Look elsewhere if you
- Want branded, FDA-approved Wegovy® or Zepbound®
- Want a needle-free oral option
- Live in a state altRx does not serve
How altRx Compares
Compared with TrimRx, which starts at $149 but guarantees the same price at every dose for life, altRx is cheaper to start, especially for semaglutide. BetterMe Rx costs more ($155 for semaglutide) but includes a needle-free tablet option. If you want branded medication, Ro offers FDA-approved options including the Wegovy® pill at a higher cost. For annual-plan pricing, our semaglutide and tirzepatide rankings list providers that go lower if you prepay a year.
altRx FAQ
altRx prescribes through licensed clinicians after an online medical intake and ships from licensed pharmacies. As with any compounded GLP-1 provider, the medication itself is not FDA-approved.
Semaglutide starts at $89 a month and tirzepatide at $149 a month, with lower monthly rates on 3-, 6- and 12-month semaglutide plans. There is no membership fee.
No. altRx is self-pay, with no insurance needed. You can split payments with Affirm, Klarna or Afterpay.
Yes. Month-to-month plans can be cancelled anytime. Prepaid multi-month plans are paid up front, so check the terms before choosing one.
No. altRx focuses on compounded semaglutide and tirzepatide. For branded options, compare Ro or MEDGm in our GLP-1 ranking.
Our Verdict
9.90 / 10 · Outstanding
altRx is the easiest low-cost way into GLP-1 treatment we have found: $89 for semaglutide or $149 for tirzepatide, fully online, no membership and cancel anytime, with free two-day delivery. It is our #1 GLP-1 pick for 2026. Go in knowing the medication is compounded rather than FDA-approved, confirm the price at your target dose, and check that altRx serves your state.
See the full Best GLP-1 Providers ranking →About the author
Written by the TreatmentPick Editorial Team, a non-clinical research team that compares online treatment providers using only what each provider publishes. Facts were last checked on 2026-11-10. See how we review.